Abstract
SYNTHESIS, CHARACTERIZATION AND ANTI-MICROBIAL ACTIVITY OF AZOMETHINE DERIVATIVE OF 2-AMINO-2-ETHYL-1, 3-PROPANEDIOL AND IT’S METAL COMPLEXES

P. Malleswarareddy*, K. Sudhakar Babu, V. Krishnamurthy Naik, B. Ramu and K.M. Reddy

ABSTRACT

In this present investigation we have synthesized cobalt and copper azomethine metal complexes. Azomethine is a derivative of 2-amino-2-ethyl-1,3-propanediol prepared by condensation with vanillin. Azomethine and metal complexes were characterized by elemental analysis, electronic spectra, vibrational spectra, nuclear magnetic resonance, TGA, and Electron Spin Resonance, All these data confirms that the copper complexes exhibit octahedral geometry. These complexes exhibit high potent anti microbial activity against Bacillus cereus (MTCC – 1272) Gram positive bacterium and Salmonella typhi (MTCC – 3224) Gram negative bacterium.

Keywords: 2-Amino-2-Ethyl-1, 3-Propanediol, azomethine ,Octahedral geometry and Anti microbial activity.


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