Abstract
MANIFESTATIONS AND PATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUS IN NEONATES AND ADULTS - A COMPREHENSIVE REVIEW

Angelo Soukovelos*

ABSTRACT

Systemic lupus erythematosus (SLE) is a chronic and diversified autoimmune inflammatory disease that can affect any part of the body. SLE is an etiological condition that has many attributes and symptoms that are indeterminate. In recent years, interest in the disease has been stimulated and, as a result of improved screening methods, the number of known cases has risen dramatically. It is clear that we can no longer contend that this is an uncommon illness. The bulk of SLE pathology is associated with multi-tissue deposits of immune complexes, which can lead to supplementation and other inflammatory mediators. The signs range from person to person and can be mild, moderate or extremely extreme in adults as well as in neonates, depending on the part of the body that is affected.

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