European Journal of Biomedical and Pharmaceutical Sciences

NEWS ON THE HISTOPATHOLOGICAL STUDY OF CERVICAL ADENOPATHIES IN ANTANANARIVO, MADAGASCAR

Mananjara Nandrianina R, Andriamampionona Ginnot B*, Randrianarivelo Hariniaina JA, Fare Avvisoa TS, Razanakoto Georges FA, Ramarozatovo Njakasoa P, Razafindrakoto Rex MJ, Rakotoarisoa AHN and Rakoto FA

ABSTRACT

Introduction: Cervical lymphadenopathy is the first cause of cervical mass in children and adults alike. Admittedly, various retrospective epidemiological studies have already been carried out in the ENT and cervico-facial surgery departments of Antananarivo, but it turns out that our practitioners still face difficulties in the management of these lymphadenopathies. The objective of our study was to determine the histopathological profile of cervical lymphadenopathy in Antananarivo. Materials and method: This is a descriptive, multicenter, retrospective study performed in the ORL-CCF departments of the various hospitals in Antananarivo over a 12-month period from January to December 2018. The study included all patients who underwent lymph node biopsy with an anatomopathological result. The variables studied were age, gender, duration of consultation, characteristics of lymphadenopathy and anatomopathological findings. Results: We selected 73 cases with an average age of 28.72 years, a sex ratio of 0.86. The predominant symptom was lateral cervical tumefaction with no associated signs (54.79%). The duration of consultation ranged from 1 to 38 months. Tuberculosis was the first etiology (38.35%), followed by lymphomas (26.02%), followed by nonspecific adenitis (23.28%), and metastatic adenopathies (9.58%). Conclusion: The complete ENT examination with nasofibroscopy should be systematic in front of cervical lymphadenopathy. The emergence of HIV-AIDS in our country should lead to a change in diagnostic and therapeutic behavior in the presence of nonspecific cervical lymphadenopathy.

Keywords: lymphadenopathy, neck, histology, lymphoma, tuberculosis.