European Journal of Biomedical and Pharmaceutical Sciences

COMPARISON THE DIFFERENCE BETWEEN ACUTE RETINAL NECROSIS AND PROGRESSIVE OUTER RETINAL NECROSIS

Samia Iqbal*, Nawar Jan Anwar, Muhammad Mujahid and Rashida Riaz

ABSTRACT

Necrotising retinopathies can be visually destroying. Generally it is related with the viral family Herpesviridae and observed in both immune‐competent and immunocompromised hosts, potential inconveniencil of necrotising retinopathies include normal retinal dystrophy with or without macular inclusion, optic neuropathy and eventually, optional retinal detachment. Examples include progressive outer retinal necrosis, acute retinal necrosis and cytomegalovirus retinitis. If diagnosed early and treated aggressively, visual complications can be prevented; however, there is no current consensus on the most appropriate antiviral regimen for each of the different varieties of necrotising herpetic retinopathy. This paper reviews aspects of varieties of necrotising herpetic retinopathy, including pathophysiology, treatment and diagnostic testing. Necrotising retinopathies are a group of uncommon posterior segment complications of herpetic viral aetiology. The herpetic viral family, Herpesviridae, contains many viruses, including varicella zoster virus (VZV), herpes simplex virus (HSV) types 1 and 2, and cytomegalovirus (CMV). Necrotising retinopathies caused by members of Herpesviridae include acute retinal necrosis (ARN), progressive outer retinal necrosis (PORN) and cytomegaloviral retinitis, the most common herpetic retinal necrosis being cytomegaloviral retinitis within an immune‐compromised patient population.

Keywords: .