European Journal of Biomedical and Pharmaceutical Sciences

EPIDEMIOLOGY AND CHARACTERIZATION OF LUMBY SKIN DISEASE IN NORTH EASTERN OF EGYPT

Adel M. El-Kattan*

ABSTRACT

Lumby Skin Disease (LSD) is an insect born, notifiable, transboundary eruptive viral disease belonging Capripox viruses. Mostly affect cattle and causing a significant impact on cattle industry, trade and food security. Our work aimed to study some epidemiological data about LSD including the isolation serological and molecular characterization of its causative agent in the area of study. Samples were collected from some cow herds at the area of Gelbana & sahel al-Tina villages, North Sinai Governorate. The causative virus was isolated on chorioallantoic membrane (CAM) and MDBK cells. Polymerase Chain Reaction (PCR) identified the isolated virus as LSD. Protective viral neutralizing antibodies were found in 19/23 (82.60%) and 5/27 (18.51%) of previously vaccinated and non vaccinated animals respectively. The overall morbidity and mortality rates were 21.25% and 2.5% respectively. Other risk factors as age, gender and vaccination status were studied revealing that, clinically, the disease occurrence is more frequent in younger (27.5%), male (22.85%) and non-vaccinated animals (32.55%). In conclusion, proper extensive vaccination process using a local efficient LSD virus isolates, further education of herd owners about the etiology and transmission of LSD and Strict monitoring of animal in and out movements in the area of study including Quarantine should be employed by veterinary authorities in order to reducing the circulation of LSD.

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