European Journal of Biomedical and Pharmaceutical Sciences

ASPECTS OF FORMATION OF POPULATION IMMUNITY TO SARS-CoV-2

Rakhimov R.A., Khikmatullaeva A.S., Ibadullaeva N.S.*, Ismailov U.Yu., Rakhimova V.Sh.,
Abdukadirova M.A., Lokteva L.M.

ABSTRACT

A comparative analysis of the registered incidence of COVID-19 and the dynamics of the formation of the level of population immunity to SARS-CoV-2 in two contrasting regions of the Republic of Uzbekistan (Andijan and Khorezm regions) was carried out. The registration of patients with COVID-19 in the country was carried out on the basis of positive test results for the presence of SARS-CoV-2 RNA, using the PCR method. To study population immunity, the WanTai SARS-CoV-2 Ab Rapid test (China) was used 1290 healthy people were examined in August 2020 and 148 people in February 2021. In the Andijan region, the registered incidence was 1.4 times significantly higher (p<0.001) than in the Khorezm region. The higher level of population immunity in the Khorezm region in the 5th month of the pandemic is explained by intensive external migration at the beginning of the pandemic. The high population density contributed to the intensive growth of population immunity in Andijan region. The actual incidence of COVID-19, in the Andijan and Khorezm regions, was 608.6 - 850.0 times higher than it was revealed by PCR testing.

Keywords: COVID-19, SARS-CoV-2, Andijan region, Khorezm region.