European Journal of Biomedical and Pharmaceutical Sciences

DEMOGRAPHY, CLINICAL PROFILE AND OUTCOME OF 100 CASES OF COVID-19: A CROSS SECTIONAL OBSERVATION IN DHAKA

Saha S.K., Nasir M.*, Mahmood T., Mukta M., Hasan R., Nuruzzaman M. and Majumder T.K.

ABSTRACT

Objective: From late December’19 till the end of August 2020, in these nine months, the world has lost more than eight hundred thousand people due to the COVID-19 pandemic. Clinical data on COVID-19 in Bangladesh is less. The objective of our study was to evaluate demographic and clinical profile within a defined period among COVID-19 Bangladeshi Patients in a Tertiary Care Private Medical College Hospital in Dhaka. Method: This observational study was conducted in the Department of Medicine, BAMCH for the period of four months (July 2020 to October 2020) following ethical approval. Total 100 Patients were diagnosed with COVID-19 cases either by real-time polymerase chain reaction (RT-PCR) positivity or by clinical features along with typical HRCT chest findings. Informed written consent was ensured before participation. Collected data were entered in pre-determined case record form (CRF)and subsequently analyzed by SPSS-20. Result: Among these 100 patients, the mean age was found to be 53 years. The highest percentage of patients (44%) belonged to 41-60 years of age. Regarding gender distribution, two-third of patients were male (70%) & one-third of patients were female (30%). The predominant symptoms of our enrolled patients were fever (88%), cough (80%), dyspnea (58%), and fatigue (48%). Around half of the patients had been suffering from Hypertension (54%) and Diabetes (47%). Almost half of our patients belonged to moderate severity (60%). The duration of hospital stay was from 1-36 days the mean was 7 days. There was a significant difference between severe and non-severe cases (p-value <.01). Conclusion: As this was early data, showing the epidemiological and clinical profiles of Bangladeshi COVID-19 patients hospitalized at a Private Hospital in Dhaka, the rate of RT-PCR positive cases were high without history of contact or exposure with infected person. The study reassured the vulnerability of elderly males in Bangladeshi population. Nationwide dissemination of study results including asymptomatic cases is crucial to limit the community transmission.

Keywords: Coronavirus, COVID-19, clinical profile, demography, Bangladesh, pandemic.