European Journal of Biomedical and Pharmaceutical Sciences

A REVIEW ON FAST DISSOLVING TABLETS

Shubhangi Zanak Jadhav*, Dr. Nishan Bobade, Vivek Kharbade and Abhishek Kadu

ABSTRACT

Oral delivery is currently the gold standard in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. Oral dosage form and oral route are the most preferred route of administration for various drugs has limitations like first-pass metabolism, psychiatric patients, bedridden and uncooperative patients. FDTs are disintegrating or dissolve quickly in the saliva without a need of water. Fast dissolving tablets are designed to dissolve in saliva remarkably faster, within a few seconds (less than 60 seconds), and those are real fast-dissolving tablets. FDTs formulations contain super disintegrate to enhance the disintegration rate of a tablet in the ducal cavity. FDTs have disintegrated quickly, absorb faster so, in vitro drug release time improve and this property of drugs (dosage form) enhanced bioavailability. In this review contain brief information about FDTs including definition, advantages, salient features of FDTs, limitations, challenges to developing FDT, technologies, evaluation parameters, marketed formulations of fast dissolving tablets, etc.

Keywords: Fast dissolving tablets, Superdisintegrants, Evaluation of fast dissolving tablets, Fast dissolving technologies.