European Journal of Biomedical and Pharmaceutical Sciences

AN OVERVIEW ON CHEMISTRY AND VARIOUS BIOLOGICAL ACTIVITIES ON MESOIONIC CHALCONES

Dr. Konda Ravi Kumar*, D. Anusha Reddy, B. Sai Keerthana, B. Jeevan Reddy

ABSTRACT

Privileged structures have been widely used as an effective template in medicinal chemistry for drug discovery. Chalcone is a common simple scaffold found in many naturally occurring compounds. Many chalcone derivatives have also been prepared due to their convenient synthesis. These natural products and synthetic compounds have shown numerous interesting biological activities with clinical potentials against various diseases. This review aims to highlight the recent evidence of chalcone as a privileged scaffold in medicinal chemistry.These chalcone derivatives have shown important antimicrobial, antifungal, anti-mycobacterial, antimalarial, antiviral, anti-inflammatory, antioxidant, antileishmanial. This review highlights the synthesis and pharmacological properties of chalcone derivatives.

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