Abstract
CASE REPORT: EXTRANODAL NK/T CELL LYMPHOMA, A RARE ENTITY

Ankita Goel*, Rajan Bhatnagar, Dhiraj Kishore, Ravi Tandon, Mahima Yadav and Amrita Ghosh

ABSTRACT

Extranodal natural killer/T-cell lymphoma, nasal type (NKTL) is a rare disease with highly aggressive clinical course and poor prognosis. The most common site of presentation is upper aerodigestive tract. The disease may disseminate to various extranasal sites like intestine and other organs but bone marrow infiltration is uncommon. The treatment is largely determined by the extent of disease. Prompt recognition is essential as early treatment is necessary for survival. The efficacy of conventional anthracycline containing regimen is disappointing because of frequent expression of multidrug resistant P- glycoprotein. L-asparaginase containing regimens have significantly improved the efficacy and prognosis for patients with ENKTL. This case report presents a case of Extranodal natural killer/T-cell lymphoma, nasal type, its clinical presentation and diagnostic challenges.

Keywords: Natural killer/T-cell, Anthracycline, L-asparaginase, Lymphoma.


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