European Journal of Biomedical and Pharmaceutical Sciences

COMPARATIVE EVALUATION OF PH CHANGES OF SALIVA USING PROBIOTIC AND CHLORHEXIDINE MOUTHWASH IN CHILDREN – A SHORT TERM CLINICAL STUDY

Dr. Prathyusha P., Dr. Amith Adyanthaya, Dr. Nazreen Ayub K.*, Dr. Sangeetha C. R., Dr. Swetha S. Nair, Dr. Risana K.

ABSTRACT

Objectives: The aim of the study is to evaluate and compare effect of Probiotic mouthwash and Chlorhexidine containing mouthwash on salivary pH in children. Method: The study was conducted over a period of one month among 40 healthy school children aged between 6-12 years. The subjects who fulfilled inclusion criteria were selected and randomly divided into 2 groups namely probiotic and chlorhexidine groups. Saliva was collected immediately after rinse (baseline), 15 mts after rinse, 30 mts after rinse and pH of each salivary sample was recorded using pH meter. Statistical analysis was done using unpaired t test. P-value <0.05 was considered statistically significant. Result: There was a significant increase in the pH of salivary sample in both Group A and Group B after the mouth rinses. Group A shows minimum increase in the salivary pH after the immediate, 15 and 30 min when compared to Group B. Comparing 2 groups, there was statistically significant difference between Probiotic mouth wash and Chlorhexidine gluconate mouth wash. Conclusion: The study conducted shows beneficial effects of probiotics in providing an alkaline environment which is conducive to oral health of children.

Keywords: dental caries; probiotics; salivary pH.