European Journal of Biomedical and Pharmaceutical Sciences

EVALUATION OF ANTIOXIDANT ACTIVITY, GC-MS AND FTIR PROFILING OF METHANOL STEM BARK EXTRACT OF MORINDA CITRIFOLIA

Nnaoma Ikenna E, Anyanwu Chioma N*, Unegbu Chika C and Ajah Obinna

ABSTRACT

This study was aimed at the elucidation of the bioactive compounds present in methanol extracts of Morinda citrifolia stem bark using Fourier transform infrared spectroscopic (FTIR) and Gas chromatography–mass spectrometry (GC-MS) techniques. The FTIR spectroscopic studies revealed the presence of these functional groups: amines, phenols, carboxylic acids, alcohols, alkenes, alkanes, and aldehydes in the extract. The GC-MS mass spectra of the identified compounds were compared with those of the National Institute of Standards and Technology database library. The results confirmed the presence of 25 compounds while 11 compounds had scientific backings about their biological activities as revealed in this present study. The presence of these bioactive compounds in the plant offers a platform for the traditional use of M. citrifolia in treatment of various diseases. However, the antioxidant screening of the bark extract should no activity as revealed in this study.

Keywords: Antioxidant, Functional groups, Methanol extract and Morinda citrifolia.