Abstract
A REVIEW ON BIO ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF AZELNIDIPINE IN BIOLOGICAL MATRICES

Anbu Kannan, JSK Nagarajan*, Bala Sundaram M., Bhuvaneshwaran A., Aparna Sebastian

ABSTRACT

Bioanalysis is related to the analysis of analytes (drugs, metabolites, biomarkers) in biological samples.Blood pressure (BP) can be notably decreased by using therapy the use of antihypertensive which reduce bp and the associated target organ damage. quantification of the drug in various pharmaceutical dosage form and in biological matrix in short analytical time this overview includes most latest strategies consisting of various spectroscopy,potentiometry, chromatography [High-Pressure Liquid Chromatography, Liquid ChromatographyElectron Spray Ionization-Tandem Mass Spectrometry, Ultra-Performance Liquid Chromatography, Ultra-Fast Liquid Chromatography] and different azelnidipine techniques for numerous prescription drugs and organic matrix.

Keywords: Bioanalytical methods; azelinidipine; mechanism of action; pharmacodynamic-pharmacokinetic, estimation


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