European Journal of Biomedical and Pharmaceutical Sciences

APPRAISAL ON ORAL DISINTEGRATING TABLET: A REVIEW

Manasi Akash Dighe*, Nikita Dilip Bachhav and Rohit Sanjay Bhamare

ABSTRACT

Fast disintegrating tablets (FDTs) are those solid dosage forms when put on tongue, disintegrate or dissolve instantaneously, releasing the drug, within a few seconds without the need of water. Fast disintegrating tablets (FDTs) aim for designing dosage forms, convenient to be manufactured and administered, free of side effects, offering immediate release and enhanced bioavailability, to achieve better patient compliance. Fast disintegrating tablets have been formulated for pediatric, geriatric, and bedridden patients and for active patients who are busy and traveling and may not have access to water. Such formulations provide an opportunity to persons which have difficulty in taking conventional oral dosage form.(viz., solutions, suspensions, tablets, and capsules).The current article is focused on ideal requirements, need for development of FDTs, superdisintegrants employed, various technologies developed for FDTs, patented technologies like Wowtab, Durasolv, Orasolv, Flashtab, Zydis, Frosta technology, Sheaform, Ceaform technology, Nanocrystal technology which have gained importance in international market, evaluation methods and various marketed products.

Keywords: Fast disintegrating tablets (FDTs) are those solid dosage forms when put on tongue, disintegrate or dissolve instantaneously, releasing the drug, within a few seconds without the need of water. Fast disintegrating tablets (FDTs) aim for designing dosage