A MULTIDISCIPLINARY APPROACH FOR THE CLINICAL, RADIOLOGICAL, HISTOPATHOLOGICAL & SEROLOGICAL PROFILE IN PATIENTS WITH INTERSTITIAL LUNG DISEASE
G. N. Srivastava, Sujeet Kumar Karn*, Neeraj Dhameja, Ishan Kumar, Akhilesh Tiwari and Brighton M.
ABSTRACT
Background: Interstitial Lung Disease (ILD) refers to a heterogeneous group of more than one hundred distinct
lung disorders that are grouped together because they share similar clinical, radiographic, and pathologic features.
Diagnosing ILDs in India has proven to be a challenge as it is confounded by environmental and cultural factors in
the midst of infections, especially Tuberculosis. The country has a lack of resources, standardized health care and
guidelines for approach to ILD. While approaching a patient suspected to have ILD one should use a combination
of a detailed history, clinical examination, radiographic findings, pathological features and serological tests.
Method: A descriptive study designed to evaluate 50 suspected ILD with multidisciplinary approach including
clinical, radiological, serological and histopathological approaches. Results: We evaluated 50 patients (mean age
48.02 years; 54.0% females) of Interstitial Lung Diseases (ILD) with multidisciplinary approach. Connective
tissue disease related ILD (26.0%) was the most common type of ILD, followed by Hypersensitivity pneumonitis
(20.0%) and Idiopathic pulmonary fibrosis (18.0%). Sarcoidosis was diagnosed in a lesser proportion of patients
(4.0%) as compared to other studies. Conclusions:. TBLB appears to be an important diagnostic tool for the
diagnosis of DPLDs. The use of a pattern-based approach to TBLB adds to its diagnostic yield and can be helpful
in cases where open lung biopsy is not available.
Keywords: Trans-Brochial lung biopsy, serology, histopathology, radiography.
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