European Journal of Biomedical and Pharmaceutical Sciences

SWYER JAMES MACLEOD SYNDROME “AN INCIDENTAL FINDING IN A MIDDLE AGED WOMEN WITH A UNILATERAL HYPERLUCENT LUNG”

Ritamvara Oli*, J. K. Mishra, G. N. Srivastava, Saurabh Mishra, Gawthami Balu, Aparna Suresh, Aiyush Jain, Sravani Kanchi, Somya Das

ABSTRACT

Swyer-James Macleod syndrome also k/a Bret syndrome is an exceptional form of post infectious obliterative bronchiolitis usually thought to be secondary to Viral infections. It is consequence of insult abide by which it results hypoplasia and/or agenesis of the pulmonary arteries resulting in pulmonary parenchyma hypoperfusion .It is seen in association with 3.8% patients with bronchiolitis obliterans. The usual age of presentation is early childhood or sometimes adulthood. Patients are usually asymptomatic. The most concerning long-term effects of this syndrome is recurrent lung infections. Most patients have a unilateral involvement of the left lung primarily. In some patients with Swyer-James-MacLeod syndrome, bronchiectasis may develop proximal to bronchiolitis obliterans and is likely a sequela of chronic infection.

Keywords: Obliterative bronchiolitis, Lung hypoplasia, Lung hypoperfusion, Lung agenesis.