Abstract
ANTIBACTERIAL ACTIVITY AND MODE OF ACTION OF SELECTED PHENOLIC ACIDS AGAINST SOME PATHOGENIC BACTERIA

*Yasser M. Kamel

ABSTRACT

There has been growing concern about the emergence and spread of antibiotic-resistant bacteria worldwide, so it is important to explore alternative effective antimicrobial compounds. This work was designed to evaluate the antibacterial activities of gallic and caffeic acids against gram-positive and gram-negative bacteria with the attempt to elucidate their mode of action through estimation of various bacterial physiological indices as minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), releasing of intracellular potassium ions (K+) and membrane permeabilization. The results show that both acids inhibited the growth of both types of bacteria with various degrees and their effect on gram-negative bacteria was greater than that on gram positive. Moreover, caffeic acid had an antibacterial effect more potent than Gallic acid. The current study emphasizes the potential use of caffeic and gallic acids as a good source of new antibacterial products, particularly against gram-negative strains.

Keywords: MIC, MBC.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • EJBPS: JUNE ISSUE PUBLISHED

    JUNE 2021 Issue has been successfully launched on 1 June 2021

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT