Abstract
TRANSDERMAL DRUG DELIVERY SYSTEM: A REVIEW

Minal S. Taywade*, S. D. Pande, Jaya P. Madaghe, Pawan B. Tripathi and Roshani I. Sheikh

ABSTRACT

A Transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream. Transdermal delivery provides a advantage over injectables and oral routes by increasing patient compliance and avoiding first pass metabolism respectively. Transdermal patches deliver the drugs for systemic effects at a predetermined and controlled rate. Through a diffusion process, the drug enter the bloodstream directly though the skin. Since there is high concentration on the patch and low concentration in the blood, the drug will keep diffusing into the blood, for a long period of time, maintain the constant concentration of drug in the blood flow. This review article provides an overview of TDDS, its advantages over conventional dosage forms, drug delivery routes across human skin, penetration enhancers, various components of Transdermal patches, types of Transdermal patches.

Keywords: Transdermal Drug Delivery, Patches, Types, Drug In Adhesive.


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