Abstract
DETERMINING THE EFFECTS OF PROBIOTIC STRAINS IN COMBINATION WITH ANTIBIOTICS AGAINST PATHOGENIC ORGANISMS

Dhanisha Shah and Kinnari N. Mistry*

ABSTRACT

Probiotics are well known to show positive health effects upon the humans and animals are now being used as medicines to combat the diseases due to their ability to inhibit the pathogenic microorganisms. The aim of our study was to determine the effect of lactobacillus and Bifidobacteria sp when combined with different antibiotics against E.coli, S.aureus, P.aeroginousa, Bacillus sp. Kirby Bauer disc method was used for evaluating the zone of inhibition alongside the agar well diffusion method. Bifidobacteria sp and L.acidophilus showed better enhancement of zone in combination with antibiotics in most of the cases than antibiotics or probiotics alone. These results suggest the combinatory effect of antibiotics and probiotics could increase the efficacy of bacterial disease treatment. Probiotics can be a great approach in the future for aiding not only the food-borne disease but other bacterial infection as well when combined with antibiotics.

Keywords: Probiotics; Antibiotics; Lactobacillus; Bifidobacteria.


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