European Journal of Biomedical and Pharmaceutical Sciences

PRESCRIPTION PATTERN FOR INFERTILE WOMEN WITH POLY-CYSTIC OVARY SYNDROME (PCOS) IN A TERTIARY CARE HOSPITAL

Dedeepya S.*, Nazneen Banu, Jadukore Chaya, M. Shivani and Ranjitha Kotr

ABSTRACT

Introduction: The main aim of the study is to focus on the prescription pattern for infertile women with PCOS in the tertiary care hospital. The target of the prescription pattern for infertile women with PCOS is to stop the occurrence of PCOS conditions. The time of initiating PCOS drugs therapy should be determined in keeping with the extent of severity. The study on prescribing pattern improves the standard of prescription writing, so a study of drug prescribing pattern has relevancy within the present scenario. The main purpose of drug utilization research is to evaluate the rationality of drug use. The objective of the study was to study the prescribing patterns of medication used for PCOS conditions and to spot, which drug is commonly prescribed at that hospital. Materials and methods: This is a prospective observational study conducted for six months. The study was conducted at GLENEAGLES AWARE GLOBAL HOSPITAL LB. NAGAR. Patients from the outpatient department of the hospital for six months are enrolled. PCOS female patients visiting the gynecologist are evaluated, diagnosed and prescribed with suitable therapy. Using a suitable designed data collection form, the details were collected from patient demographics, prescription chart, lab data, progress chart, medical records, doctor’s notes, nursing notes. Results: According to the study carried out the no of females enrolled were 50. The age distribution of patients are 20-23(26%), 24-27(44%), 28-31(20%), and 32-35(10%). 62% Of females were homemakers and the rest 38% were working women. Irregular menstrual pattern was seen in 90% of the females and 10% of females had a regular menstrual pattern. Type-1 infertility 32(68%) was dominant over Type-2 16(32%). BMI index of the 50 members was 18(36%) of females had normal BMI, 6(12%) were underweight, 16(32%) were overweight and 10(20%) were obese. On whole of using both single and combination treatments LOD was given to 6%, metformin was given to 19%, Gonadotropins was given to 33.5%, clomifene citrate or clomid was given to 67.5% and oral contraceptives were given to 93.5%. Thus Oral contraceptives are the most commonly used drugs according to our study after oral contraceptives the second common drug was clomifene citrate and futherly used were gondaotropins and metfromin and LOD was the least common used procedure for treatment of infertile women with PCOS. Conclusions: The study consists of 50 infertile women with PCOS for atleast 2 years of infertility. It is based on a variety of factors like food habits, being overweight or obese, less exercise and poor wellbeing. The prescription pattern is rational and it adheres to the standard treatment rule thus, the treatment was cost-effective and helpful for fast recovery patients with PCOS. The recommending design was objective and it adheres to the standard treatment rules. Other than test size doesn't mirror the real population size and remedy design in the entire state or country. Most of the studies conducted on PCOS have similar results as it is the most common endocrinopathy disorder affecting reproductively aged women. Infertile women who were obese/overweight along with unhealthy lifestyle habits, lack of awareness to maintain a normal BMI are more prone to the syndrome. The prescription pattern of PCOS women mostly involved combination therapy in which most women were given OC then CC CC and CC with metformin along with OC, and also were given OC then CC with gonadotropins. Lifestyle modifications including diet, exercise and weight management are strongly recommended for patients to avoid worsening the syndrome.

Keywords: Polycystic ovary syndrome (PCOS), Infertile women, Prescription pattern.