A SHORT REVIEW ON “LIPOSOMES”
*Priya Bindal, Pankaj Chasta, Dr. Gaurav Kumar Sharma and Dr. Kaushal Kishore Chandrul
ABSTRACT
Liposomes, sphere – shaped vesicles consisting of one or more phospholipid bilayers, approved for clinical use in 1995. The term Liposome means lipid body. It has been derived on the basis of subcellular particles, Ribosomes. Their size ranges from 25 to 500nm. Liposomes present as an attractive delivery system due to their flexible physiochemical delivery considerations. In this review article, we discussed about Liposome, these are one among the various drug delivery system used to target the drug to particular tissue. The various other drug delivery includes noisome, microparticles, released erythrocytes, pharmacosomes etc. Research on liposome technology has progressed from conventional vesicles to “Second -generation liposomes”, in which long circulating liposomes are obtained by modulating the lipid composition, size and charge of the vesicle. This paper summarizes exclusively components, methods of preparation, Drug delivery etc.
Keywords: Drug delivery system using liposomes, advantages and disadvantages of liposomes, applications, Mechanism, Method of preparation of liposomes.
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