Abstract
CHEST CT FEATURES OF COVID-19 PNEUMONIA PATIENTS WITH CHRONIC KIDNEY DISEASE

Dr. Nabanita Deka, Dr. Unais Mubarak* and Dr. Bhaskar Das

ABSTRACT

This paper was intended to describe the High resolution characteristics of coronavirus disease 2019 (COVID-19) patients with known chronic kidney disease (CKD) history. A total of 200 patients were included in our retrospective observational study. Results and observations: Majority of patients with CKD (95.4%, 62/65) had more abnormal High Resolution Computed Tomography (HRCT) findings compared to patients without CKD (72.6%, 98/135). Diabetes was found to be the leading cause of CKD (29/65) with hypertension (12/65) being the next most common cause. The most common findings were GGOs (76.25%), ILST (70%) and sub-pleural fibrotic lines (68.12%). Out of 53.75% cases showing consolidation, it was seen more commonly in CKD patients at 75.8% as compared to 39.8% in non-CKD patients. Out of a total 18 patients showing pleural effusion, 16 patients were from the CKD group. Average CT Severity Score (CTSS) of CKD patients were higher (21/25) as compared to non CKD patients (13/25).Out of the 65 CKD patients, 4 patients (6.15%) died compared to only one patient dying out of 135 among non-CKD patients. 23.07% of the CKD patients needed ICU admission with 15.38% of them requiring mechanical ventilation which was significantly higher than 9.63% needing ICU admission and 4.44% needing mechanical ventilation in the non-CKD group. Patients in the CKD group showed lesser improvement with 28% CKD patients having severe disease during initial presentation which showed improvement to only 20% after the end of 14 days, however at the end of 25 days there was improvement to 4%. Conclusion: In this era of COVID-19 pneumonia, more care should be taken for those who are having comorbidities like CKD, as those patients are more prone to serious pulmonary complications and have slower disease resolution.

Keywords: COVID-19, Chronic kidney disease, HRCT, Ground Glass Opacities.


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