European Journal of Biomedical and Pharmaceutical Sciences

SYSTEMIC LUPUS ERYTHEMATOSUS WITH CNS LUPUS IN THE FORM OF VASCULITIS, GROSS ASCITES, PLEURAL EFFUSION, ANEMIA OF CHRONIC DISEASE AND UTI

Ankita Goel*, Deepak K. Gautam, Abhishek Pandey, Anish Saha, Mukti Prakash Meher, Ashis Gupta, Disha Arora and Pankhudi Priya

ABSTRACT

Systemic lupus erythematosus (SLE) is a complex autoimmune disease with a varying clinical phenotype and prognosis from mild to life threatening. SLE needs to be differentiated from its mimickers sharing similar clinical and laboratory features, as Early management is crucial to prevent involvement of various organs. Also, it is important to establish the severity and potential reversibility of the illness and to estimate the possible consequences of various therapeutic interventions. Interventions including steroids, immunosuppressants, plasmapheresis, some biologics, and vaccination have shown efficacy in reducing mortality rates, though still higher than general population.

Keywords: Lupus, autoimmune, prognosis, SLE, steroids, mortality.