Iyanu V. Olateju MD, MHA*, Omotola Emmanuel MD, MBA, Ruth E. Pius MBBS, Adejoke O. Dada-Bello M.B.Ch.B and Peace C. Asuzu MD, MPH


Since the beginning of the Coronavirus outbreak in December 2019, there have been many comorbidities and complications associated with this respiratory illness. Among these are cardiovascular diseases (CVD). Multiple studies have reported an exacerbation of pre-existing cardiovascular conditions in COVID-19 patients, as well as increased morbidity and mortality. Other studies reported an association of COVID-19 with the incidence of cardiovascular diseases. Either way, the inflammatory process involved in the pathogenesis of COVID-19 infection has been reported as a potential cause of myocardial injury, especially in critically ill patients. This review aimed at investigating the pathogenesis and impact of COVID-19 on patients with pre-existing cardiovascular diseases. Beyond establishing an association, we also focused on the mechanisms of myocardial injury in COVID-19 patients and the management approach. We searched PubMed and Google Scholar for this review from May 1, 2016, through May 1, 2021. We selected publications reporting the pathogenesis, association, and outcome of the disease process in COVID-19 patients with cardiovascular diseases and finalized 14 critically appraised articles for this review. After a careful analysis, most studies reported an exacerbation of the disease process in covid-19 patients with pre-existing cardiovascular diseases. This exacerbation was associated with an exaggerated inflammatory response to the coronavirus, which caused a myocardial injury. Few studies indicated that myocardial injury is not limited to COVID-19 patients and could also occur in any critically ill patient. In conclusion, COVID-19 patients with cardiovascular conditions are at increased risk for complications and mortality and, therefore, should be monitored closely and treated promptly.

Keywords: cardiovascular disease, comorbidities, COVID-19.

[Full Text Article]


Forgot Password  |  Register


Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation


    MAY 2023 Issue has been successfully launched on 1 MAY 2023.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.


  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.


UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS


Copyright From

Covering Letter

                        Author Instruction