Abstract
WEGENER'S GRANULOMATOSIS WITH POLYANGITIS AND RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS: A CASE REPORT

Reshma Rajan* and Shaiju S. Dharan

ABSTRACT

Wegener’s granulomatosis (WG) is an autoimmune inflammatory condition. It is often a rapidly progressive and potentially fatal disease. A 47 year old with H/O liver transplantation donor admitted in General Medicine department complaining Haemoptysis, chest pain and Haematuria. CT Thorax Scan done and which shows Pulmonary Haemorrhage. Also serum creatinine was elevated rapidly, Kidney biopsy and c-ANCA was positive, which was successfully treated with high-dose steroids, rituximab and plasmaheresis. Her clinical life was complicated with rapidly worsening kidney condition which has been associated with Wegener’s granulomatosis flares. The recognition of multisystem disease is critical for diagnosing Wegener's vasculitis. Diffuse alveolar haemorrhage and rapidly progressing glomerulonephritis are the fulminant manifestation of Wegener’s granulomatosis, in which case immediate and aggressive treatment with pulse steroids, Rituximab Injection and plasma exchange can be life-saving.

Keywords: elevated rapidly, Kidney biopsy and c-ANCA.


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