European Journal of Biomedical and Pharmaceutical Sciences

RETROSPECTIVE CASE SERIES STUDY OF HEMATOLOGICAL PARAMETERS OF DENGUE FEVER PATIENTS FROM THE BANGLADESHI POPULATION

Mohammad Asaduzzaman*, Farha Matin Juiana, Md. Shakhawat Hossain, Md. Readul Amin, Md. Ikramul Haque, Saad Ahmed and Tasnuva Ferdous

ABSTRACT

Background: The objective of the present study was to evaluate the haematological parameters as screening markers for differentiating patients with dengue fever. Methods: This study was a retrospective case series study in Dhaka, Bangladesh. All data of patients of dengue infection from January 2019 to August 2019 was retrieved anonymously from computerized medical records including laboratory results. For statistical analysis, all analysis was performed by software GNU PSPP stable release 1.4.1/September 5, 2020. Result: The results showed that among 250 confirmed patients with dengue infection, MCV, MCH, HCT and PCT were significantly lower in patients with dengue fever (DF). The RBC count was found to be a little bit lower in patients with dengue infection. Hb was found to be much lower in female patients than in males as per standard limit. The platelet count was significantly lower in patients with dengue infection compared to patients with non-dengue infection. Conclusion: Alteration of haematological parameters can be combined with other clinical and laboratory markers to help physicians make an early diagnosis of dengue fever on the first day of admission to help closely monitor patients with dengue and prevent developing dengue haemorrhagic fever (DHF).

Keywords: Dengue, Hematological parameters, Markers.