Abstract
QUALITY ASSESSMENT OF LAKSHADI GUGGULU VATI: A POLYHERBAL FORMULATION

Anjali Upadhyay*, Rohit Singh, Robin Badal, Pramod Yadav and P. K. Prajapati

ABSTRACT

Lakshadi Guggulu Vati (LGV) is one of the widely used poly herbal formulations in Ayurvedic clinical practice since decades for the treatment of various conditions like fractures (Kanda Bhagna), pain (Ruja), dislocation of joints (Sandhi Bhagna) etc. However, comparative analysis of different marketed samples of LGV needs to be carried out to ensure uniformity in the quality of raw drugs and pharmaceutical process. In this germane, present study has been carried out with an objective to generate and compare the analytical profile of different marketed samples of LGV and validate its quality standards as per official publications. Various marketed samples of LGV have been procured and comparative evaluation for their quality control parameters along with HPTLC finger printing as per guidelines of Ayurvedic Pharmacopoeia of India (API) have been carried out. The study revealed significant variation in values of quality control parameters of all four marketed samples of LGV. It can be inferred from the study that dissimilitude in quality control parameters of all marketed sample is evident. Therefore, analytical evaluation and standardization of raw drugs of all patent as well as classical formulations should be performed to optimize the final product quality according to the standards, which would otherwise affect the therapeutic activity of the finished products.

Keywords: HPTLC, Lakshadi Guggulu Vati, Phytochemical screening, Quality control.


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