European Journal of Biomedical and Pharmaceutical Sciences

COENZYME Q10 AND NEUROPROTECTION

*Italo Giuffre’ MD PhD

ABSTRACT

Purpose: This is an open, prospective study about the neuroprotective effect of oral administration Coenzyme Q10 in patients affected by open-angle glaucoma. Patients and Methods: We enrolled 20 patients (10 males, 10 females) affected by open-angle glaucoma under monotherapy. They received oral supplementation of Coenzyme Q10 two tablets per day. At baseline and time 3, 6, 9 and 12 months they had a complete ophthalmological assessment and visual field test by Humphrey 30-2. The statistical analysis was performed by Student t-test. The results were considered significant at p=0.05. Results: All the patients enrolled completed the study and they did not need any laser a/or surgery. The campimetric data changed from S1 to S0 according to Glaucoma Staging System (p=0.05). Conclusion: This is a pilot study about the neuroprotective effect of oral administration Coenzyme Q10.

Keywords: Coenzyme Q10, neuroprotection, visual field test.