European Journal of Biomedical and Pharmaceutical Sciences

CORRELATION OF DURAL TAIL SIGN OF MENINGIOMAS ON MRI WITH HISTOPATHOLOGICAL GRADINGS

Chaudhary SR, M.S and Sah RG, Ph.D

ABSTRACT

Meningiomas are found to be most frequently slow-growing tumors, and presents with symptoms that are rarely precipitous, but more often subtle in nature. During physical examination it show paresis, memory impairment, other cranial nerve deficit, visual field deficit, paresthesia, aphasia, papilledema, low visual acuity, decreased level of consciousness, nystagmus and diminished hearing. Magnetic Resonance Imaging (MRI) of the brain in patient with intracranial meningiomas has been found to be useful in providing details about the diseases. Meningiomas arise from the arachnoid cap cells and are considered to be benign tumors in adults. The prevalence of dural tail sign in meningiomas ranges from 52 to 78%. The aim of this study was to predict an association between the dural tail sign in contrast T1 Weighted (T1WI) MRI with histopathological grading of intracranial meningiomas. The study population included 50 patients diagnosed as having intracranial meningiomas with or without dural tail sign in contrast T1WI MRI, who underwent surgery. Histopathological examination was considered gold standard for confirmation of meningioma. The association of dural tail sign was found to be insignificant with histopathological grading of intracranial meningiomas (WHO grade I & III) with P-value 1.000. The study also showed sensitivity, specificity and accuracy of dural tail sign in contrast MRI for the histopathological grading of intracranial meningiomas (WHO grade I and III) which were 53.2%, 33.3%, 48.0% and 66.7%, 46.8%, and 48.0%, respectively. Further, the present study, showed that dural tail sign was present in 54.0% and absent in 46.0% of the patients. The dural tail sign, which was seen in contrast T1WI MRI, was found insignificantly associated with histopathological grading of intracranial meningiomas. Therefore, the study concluded that the presence of the dural tail sign cannot predict the histopathological grading of intracranial meningiomas.

Keywords: Meningiomas, Dural Tail sign, Magnetic resonance Imaging, association, Sensitivity, Specificity.