BENZOXAZINE ANALOGUE CONTAINING 1,2,3-TRIAZOL MOIETY WHICH BEHAVES AS A NOVEL CLASS OF ANTIMICROBIAL AGENT
Dinkar Malik, Punam Yadav and Babita*
ABSTRACT
Benzoxazine and its compounds are frequently used as acceptable configurations for the building of biologically active
composites in organic conflation for erecting artificial composites. This prelude condensed summary about the
compounds which need to be noticed to have antimicrobial, antimycobacterial, anti-diabetic, anti-hypolipidemic,
and anti-depressant properties. It could be a useful tool for pharmacists to discover additional benzoxazine derivatives
that are more efficacious and safer. The benzoxazine shell's versatility, as well as its chemical simplicity and availability,
make it one of the most promising sources of bioactive composites. Our ideal is to incorporate the aromatic halves in a
single patch containing benzoxazine, triazole in the thirst that it'll enhance the natural exertion of the performing
composites. The new composites were synthesised in high yield, and all synthesised composites will be thoroughly
characterised using precise spectral investigations such as 1H NMR, mass, 13C NMR and IR. All synthesized composites
will be screened for their in vitro antibacterial and antifungal exertion following Cup- plate system against standard
medicines Ciprofloxacin for bacteria and Miconazole for fungi.
Keywords: Benzoxazine, Heterocyclic Moiety, Cup-plate method, IR, 1H NMR, 13C NMR, Mass Spectroscopy.
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