European Journal of Biomedical and Pharmaceutical Sciences

PLACENTAL MESENCHYMAL DYSPLASIA: RARE CASE OF NORMAL FETUS ASSOCIATED WITH INTRAUTERINE GROWTH RESTRICTION AND OLIGOHYDRAMINOUS

Dr. Sharif Jamal Hamed Salha* and Dr. Madleen Jawad Sobhe Abu Aser

ABSTRACT

Background: Placental mesenchymal dysplasia (PMD) Placental mesenchymal dysplasia (PMD) is a rare, benign placental, vascular anomaly. PMD is characterized by placentomegaly and grape-like vesicles resembling molar pregnancy on ultrasonography (USG). The differential diagnosis of PMD includes partial molar pregnancy, complete mole with the coexisting normal fetus, chorioangioma, subchorionic hematoma, and spontaneous abortion with hydropic changes. Prenatal recognition of PMD during early and late gestation could prevent unnecessary termination of pregnancy. Is an uncommon vascular anomaly of the placenta characterized by placentomegaly with a multicystic placental lesion on ultrasonography and mesenchymal stem villous hyperplasia on histopathology, Anan et al (2015). Placental mesenchymal dysplasia should be considered in the differential diagnosis of cases of multicystic placental lesions such as molar pregnancy, chorioangioma, subchorionic hematoma, and spontaneous abortion with hydropic placental changes. However, the lack of high-velocity signals inside the lesion and a normal karyotype favor a diagnosis of PMD. PMD must be differentiated from gestational trophoblastic disease because management and outcomes differ. PMD is an uncommon illness characterized by placentomegaly and aberrant chorionic villi that is frequently misdiagnosed as partial hydatidiform mole. It is, nevertheless, clinic pathologically distinct from intrauterine growth limitation is very common. (IUGR) and the mortality of the fetus this research reveals new findings. PMD examples are discussed, as well as a meta-analysis of the research. IUGR and fetal death rates are linked.

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