European Journal of Biomedical and Pharmaceutical Sciences

A RESEARCH ARTICLE ON ANTIBACTERIAL ACTIVITY OF EXTRACT OF SELLAGINELLA BRYOPTERIS L.

Dr. Prabhakar Shukla* and Dr. Swati Bala

ABSTRACT

The present study was performed to see the effect of extract of Selaginella bryopteris on Gram positive and gram negative bacteria by the agar well diffusion method. The aqueous and hydro alcoholic extracts of Selaginella bryopteris in varying amount i.e. 2,4,8,16,32,and 64 microgram were tested separately along with controls the results indicated that alcoholic extract is active against both Gram positive and Gram negative bacteria but more active against Gram negative bacteria at high concentration. The consequences of zone of inhibition of the alcoholic and hydro alcoholic extract in comparison with standard antibacterial drug (cefixime) was showed in result section. The present research work is significant on the aspect of antibacterial property estimation in an important medicinal pteridophyte species, so far least studied, It is traditionally used for curing wounds and irregular menstruation, uterine disorders and other internal injuries. It contains a variety of secondary metabolites such as alkaloids etc. due to which it can act as antioxidants, anti-inflammatory, anti-cancer, anti-allergic, antibacterial, antiviral etc.

Keywords: Selaginella bryopteris, antibacterial, Zone of inhibition.