Abstract
EXPERIMENTAL OSTEOPOROSIS: DIFFERENT METHODS AND SPECIAL EMPHASIS ON GLUCOCORTICOID-INDUCED OSTEOPOROSIS

Dalia A. Elbahy*, Mahmoud H. Abd El Reheem, Sanaa A. Ahmed

ABSTRACT

Osteoporosis (OP) is the most common systemic skeletal disease characterized by progressive bone loss and increase fragility fractures, it affects commonly the old population and females more than males. It's a worldwide challenge as OP affects more than 200 million people, in addition, it impacts a great economic burden in the aging population due to increased dependence and mortality. Glucocorticoid-induced osteoporosis (GIOP) is the most common secondary OP, that was observed with their prolonged use in the treatment of autoimmune disease, neoplasms, and organ transplantation. Designing a proper experimental model of OP is necessary to understand the pathological mechanisms and to evaluate the efficacy of new drugs. There are different methods for induction of experimental OP including: pharmacological, surgical, immobilization, diet, and transgenic. Also, combinations of these methods have the advantage of reducing the time needed for induction of OP and ensuring an apparent OP model.

Keywords: .


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: NOVEMBER ISSUE PUBLISHED

    NOVEMBER 2022 Issue has been successfully launched on 1 NOVEMBER 2022.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT