European Journal of Biomedical and Pharmaceutical Sciences

REVIEW ON “FAST DISSOLVING TABLET-A NOVEL APPROACH IN ORAL DRUG DELIVERY SYSTEM”

Simpi Sharma* and Vivek Kumar Patel

ABSTRACT

Oral drug delivery system (i.e novel drug delivery system), is the most regarded route for the administration of various types of dosage form that may have demerits like first pass metabolism, palatability of drug mostly in pediatric and geriatrics patient and unconscious patient /uncooperative patient. Fast Dissolving Tablet (FDT) aim to enhance safety, efficacy parameters and mainly improved bioavailability word of drug. These formulation have many merits such as patient compliance, ease to manufacturing and convenience. FDT takes only few second (<60 second or within 3 min.) when it come in contact with saliva in oral cavity without intake of water. Due to its faster dissolving /disintegrating properties it show quicker onset of action. This review article contains salient features, merits and demerit, various conventional techniques involved, mechanism of superdisintegrants, patented technology involved evaluation test and marketed formulation.

Keywords: Fast dissolving tablet, patented technologies, superdisintegrants, disintegration.