European Journal of Biomedical and Pharmaceutical Sciences

FLOATING TABLET: GASTRORETENTIVE DRUG DELIVERY SYSTEM

Unnati Sanjay Tribhuvan*, Pratiksha Prayag Nahar, Renuka Ravindra Joshi, Sonali Dilip Pawar, Sakshi Ashok Tribhuvan

ABSTRACT

Floating tablets lengthen the gastric house time of drugs, enhance bioavailability, and facilitate neighborhood drug delivery to the stomach. Oral route has been the most handy and typical route of drug delivery. Owing to notable healing advantages of the oral managed launch dosage varieties are being desired as the interesting subject matter in pharmaceutical discipline to carried out increased therapeutics advantages. Gastroretentive drug transport gadget is novel drug shipping structures which has an higher hand owing to its potential of prolonged holding potential in the belly and thereby enlarge gastric residence time of capsules and additionally improves bioavailability of drugs. Attempt has been made to summarize essential elements controlling gastroretentive drug shipping systems. This evaluation covers the advantages, disadvantages, marketed coaching and some patents of gastroretentive drug shipping machine and represents the floating and non-floating gastroretentive device and additionally highlights some of the current gastroretentive approaches. Recent processes to enlarge the gastric house time of drug shipping structures consist of bioadhesive systems, floating structures (low density systems), non-floating structures (high density systems) , magnetic systems, swelling systems, unfoldable and expandable systems, raft forming structures and superporous systems, biodegradable hydrogel systems.

Keywords: Uoyancy time, floating tablets, FDDS.