Abstract
ANALGESIC & ANTI INFLAMMATORY SCREENING OF CRUDE ISOLATES OF ANNONA SQUAMOSA LEAF EXTRACT

Kailash Singh Ahirwar*, Deepak Kumar Basedia and B.K. Dubey

ABSTRACT

In the present study we evaluated the anti-inflammatory and analagesic activity of crude fractions of Annona squamosa leaf methanolic extract. From the phytochemical analysis of the methanolic extract, it has been inferred that the methanol extract of Annona squamosa leaves contain the maximum number of phytoconstituents like alkaloids, glycosides, protein, flavonoids, tannins and polyphenol. By the help of column chromatography the bioactive fractions were isolated which might be responsible for the therapeutic activity. Of the total 8 fractions (F1-8), F6 and F7 indicate the presence of phenolic compounds and flavonoids. These two fractions exhibited analgesic and anti-inflammatory effect in tail flick and carrageenan- induced paw oedema models respectively. This study confirmed that flavonoid fraction obtained from Annona squamosa leaves extract are responsible for its anti inflammatory and analgesic effects.

Keywords: Annona squamosa, carageenan-induced edema, analgesic, antiinflammatory, tail flick.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: JUNE ISSUE PUBLISHED

    JUNE 2022 Issue has been successfully launched on 1 June 2022.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT