European Journal of Biomedical and Pharmaceutical Sciences

NEUROLOGICAL MANIFESTATIONS OF COVID-19: A SYSTEMATIC REVIEW

Afolarin Ishola, Subulade Adeogun, Subash Dulal, Sidra Zahid*, Obianuju Efobi MD MHA, Salomi Paul, Mohit Mathavan, Stefany Carolina Lopez Pantoja, Komal Naz Khalid, Zainab Saddiq, Devdat, Ayesha Khan, Stephen Dada, Stephen A. Akinfenwa, MD, MPH and Relfa Dellanira Proano

ABSTRACT

The commonest symptoms of infection with Covid-19 are related to the respiratory system. Yet, there have been reports that COVID-19 patients had neurological manifestations as well and the incidence of these manifestations is rising as the pandemic is on the rise. The neurological symptoms are thought to occur as a part of complications occurring secondary to a systemic disease, as a result of viral infection directly, or as a post-infectious inflammation of the nervous system and its related vasculature. The current review aims to highlight the common neurological presentations seen in Covid-19 patients. It revealed that the commonest manifestations related to the central nervous system include dizziness, headache, impaired conscious level, seizures, acute stroke, encephalitis, ataxia, and Guillain-Barre syndrome. Thus, guiding physicians in ruling out the suspicion of Covid-19 and detecting it earlier, aiding in preventing morbidity and mortality associated with it.

Keywords: Covid-19, SARS-COV2, Neurological manifestations, CNS presentations, and Seizure.