European Journal of Biomedical and Pharmaceutical Sciences

EFFICACY OF SCALING AND ROOT PLANING IN OBESE AND NON-OBESE INDIVIDUALS WITH STAGE-I PERIODONTITIS– A CLINICAL AND BIOCHEMICAL STUDY

Dr. Nikee Upadhyay*, Dr. Monali Shah, Dr. Richa Peshwe

ABSTRACT

Aim: The aim was to evaluate and compare the effect of scaling and root planing on serum resistin and serum triglycerides levels in obese and non-obese individuals with stage-I periodontitis. Settings and Design: A clinical and biochemical study conducted after the approval from Institutional Ethics Committee to evaluate the efficacy of phase-I periodontal therapy on biochemical parameters (serum resistin levels and serum triglycerides levels) in obese and non-obese individuals with stage-I periodontitis. Methods and Material: A total of 48 subjects, aged above 18 years, diagnosed with stage-I periodontitis were divided into two groups as 24 obese individuals in Group 1 and 24 non-obese individuals in Group 2. Both groups were treated with scaling and root planing at baseline and 2 months follow-up. Clinical parameters such as Gingival Index (GI), Plaque Index (PI), Clinical Attachment Level (CAL) and Clinical Periodontal Sum Score (CPSS) and biochemical parameters such as serum resistin and serum triglycerides levels were assessed at baseline and two months after scaling and root planing. Statistical analysis used: Unpaired t -test, Paired t -test and Mann Whitney U test were used to analyse the change in clinical and biochemical data. Results: On intergroup comparison, highly significant improvement (P<0.001) in all clinical parameters (PI,CAL,CPSS) was seen, whereas GI (P=0.018) showed statistical difference at baseline to 2 months. Both biochemical parameters including serum resistin and triglycerides showed highly significant improvement in both non-obese (0.007±0.01) and obese patients (0.001±0.02), while serum triglycerides levels of obese patients were 0.01±0.01 and for non-obese patients were 0.11±0.07 compared from baseline to 2 months. In non-obese patients, overall superior results were observed in terms of clinical and biochemical parameters. Conclusions: Reduction in periodontal inflammation was highly significant in non-obese patients than obese patients after Phase I periodontal treatment.

Keywords: Stage-I periodontitis, resistin, triglycerides, periodontal therapy, obesity.