ANTI-HYPERLIPIDEMIC ACTIVITY OF NUTRISLIM GREEN TEA (AYU-606) - AN AYURVEDIC FORMULATION IN HIGH FAT DIET INDUCED HYPERLIPIDEMIA IN RATS.
Sayanti Sau, Chaitra N, Dr. Triveni KC, Dr. Vatsala Guruprasad, Dr. Shivalinge Gowda KP*
ABSTRACT
The present study aimed to assess the potential Antihyperlipidemic activity of Nutrislim Green Tea (AYU-606) an
Ayurvedic formulation developed by Ayurwin Pharma Pvt Ltd Bengaluru in high fat induced hyperlipidemic rats.
The Antihyperlipidemic effects of orally administered Nutrislim Green Tea (AYU-606) powder were evaluated in
high cholesterol cocktail diet induced hyperlipidemic rats. The standard atorvastatin (10mg/kg) was administered
by oral gavage. The animals of all groups (including group II) except normal group were provided the high
cholesterol cocktail diet pellets separately for two hours daily for a period of ten days. The rats of group II receive
HCD along with normal diet. This group is used to induce hypercholesterolemia. The animals were provided with
normal diet for the remaining 20 days. The group III and IV were administered with AYU-606 by oral gavaging
daily for 20 days from 11th to 30th day of the study period. The V group animals were administered atorvastatin
(10mg/kg) by oral gavaging for a period of 20 days from 11th to 30th day of the study period. The rats administered
with HCD and AYU-606 (group III and IV) has shown a significant reduction in the serum total cholesterol level,
and significant increased levels of HDL cholesterol when compared to group II rats (HCD only). The rats
administered with HCD and AYU-606 (group III) has shown a significant reduction in the serum LDL, when
compared to group II rats. The rats administered with HCD and AYU-606 (group III) hasalso shown reduction in
the serum triglyceride level when compared to group II rats. These results validate traditional knowledge and
suggest that Nutrislim Green Tea (AYU-606) may be potentially useful for managing hypercholesterolemia and
hypertriglyceridemia.
Keywords: Hyperlipidemia, Green tea, hypertriglyceridemia, hypercholesterolemia. atorvastatin.
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