Abstract
ANTIBIOTIC PROPHYLAXIS IN CAESAREAN SECTION AT AL-SHIFA HOSPITAL GAZA STRIP, PALESTINE: A CROSS SECTIONAL STUDY

S. Dahrouj, A. Mqat, D. Albaik, O. Rabah, I. Hassan and F. Sharaf*

ABSTRACT

Background: Today, there is general agreement among the best current guidelines on the use of antibiotics as a prevention method in caesarean section (CS). CS constitutes the most commonly performed obstetric procedure in Gaza hospitals it was shown to reach 23 % in 2018, 23% of all maternal deaths were sepsis-related. Clinical research, which has never been done before in the Gaza Strip, a quality tool Control, is used worldwide to improve healthcare and also to assess the commitment of physicians and other medical staff of the applicable guidelines.. Objective: This study aims to evaluate the overall use of prophylactic antibiotics for Caesarean delivery and assessing clinicians‟ and other clinical staffs‟ adherence to the applicable guidelines., to determine the best time to administer prophylactic antibiotics for Caesarean delivery in order to reduce postoperative maternal infectious morbidity in a low resource setting, to determine the best antibiotic to use and to assess the effects of prophylactic antibiotic treatment on infectious complications in women undergoing caesarean delivery in Al -Shifa Hospital, Gaza Strip, Palestine. Methods: A cross sectional study about assessment of prophylactic antibiotic administration in caesarean section of Al Shifa Hospital was carried in period between 1st of March, 2022 and 20th of April,2022 by using a self-administered questionnaire from previous literature, the analysis included a 92 women underwent CS either elective or non-elective. We used also SPSS (version 17 for Windows) for more statistical analysis. Results: Our study included 92 participants who done CS in studied period, about 6.5% of them had postoperative infection. The result shows that there are no statistically significant association between timing of antibiotic administration, type of prophylactic antibiotic used, having a history of Chorioamnionitis or not, DM, HTN or obesity and risk of postoperative infection. There is a significant association between mother‟s age group and parity and Maternal BMI. There was no statistically significant association between number of previous CS, type of CS, type of anaesthesia given, duration of labour and postoperative infection in mother‟s age group in years. Conclusions: Prophylactic antibiotics should be used for women who will be undergoing c/s to protect them against a surgical site infection. controlling excess weight before pregnancy, as well as blood sugar and blood pressure control during pregnancy are to be considered as to mitigate the risk of SSI post C/S. The study concluded that the administration of antibiotics after C/S was also associated with better SSI prevention, SSI is less likely if time between ROM and C/S is less than twelve hours.

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