PRELIMINARY PHYTOCHEMICAL, ANTIOXIDANT AND ANTIBACTERIAL STUDIES ON THE BARK OF SPATHODEA CAMPANULATA P. BEAUV
Angela E. Peter*, Y.S.Y.V. Jagan Mohan, G. Swarajya Lakshmi, B. Ganga Rao, B. V. Sandeep, Pola Sudhakara Rao
ABSTRACT
The African tulip tree, Spathodea campanulata was selected for performing the following study. Three extracts of the bark, namely hexane, ethyl acetate and ethanol extracts were taken and subjected to preliminary phytochemical analysis, performed by standard protocols. These revealed the presence of various biochemical compounds like phytosterols, triterpenes, glycosides, saponins, flavonoids, tannins, carbohydrates, alkaloids and oils. Antioxidant capacity of the three extracts was assessed using DPPH and hydroxyl radicals, with ascorbic acid as control. The ethanol and ethyl acetate extracts showed very high antioxidant activity. Finally, the three extracts were tested for antibacterial activity, with Rifampicin as the standard drug. The ethanol and ethyl acetate extracts showed fairly good antibacterial activity against the six test organisms (Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Pseudomonas aerogenosa, Bacillus pumulis & Bacillus subtilis). Further research needs to be done to identify the specific drug candidate responsible for the observed antioxidant and antibacterial activities.
Keywords: Spathodea campanulata, Phytochemical analysis, Antioxidant activity, Antibacterial activity.
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