Abstract
A QUICK OVERVIEW OF CURCUMIN, AN HERBAL MEDICINE, IS USED IN CHEMOTHERAPY IN CARCINOMA

Sneha N. Wankhede*, Dr. Jagdish R. Baheti, Dr. Mangesh D. Godbole, Minakshi S.Warghane

ABSTRACT

Cancer is the second leading cause of death and a major public health problem. Cancer mortality remains high. Curcumin is a naturally occurring phytochemical obtained from the dried roots and rhizomes of turmeric (Curcuma longa). Shown to interfere with cell signalling pathways. Apoptosis, proliferation, angiogenesis and inflammation Most of the analogues showed excellent antitumor activity in many cell lines. Curcumin deficiency is due to low solubility, poor absorption, rapid metabolism, and elimination. Recent research has shown that several compounds and techniques to increase the bioavailability of curcumin mixed with excipients, encapsulated in a carrier, and nano formed with different bioactive. Structural analogues of curcumin, have increased efficacy and bioavailability. In this review, comprehensive literature on the anti-tumor activity of curcumin through combination therapy, structural modification, synthesis analogues and novel delivery systems is presented. Many challenges relate to curcumin as an adjuvant chemotherapeutic agent and emphasize further clinical studies.

Keywords: Curcumin, Nano-curcumin, Herbal drug, Bioavailability, Anticancer agents, Cellular pathway.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: JUNE ISSUE PUBLISHED

    JUNE 2022 Issue has been successfully launched on 1 June 2022.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT