Abstract
AN EXTENSIVE STUDY ON ALZHEIMER’S DISEASE

*Dr. L. Siddhartha and G. Harshini Priya

ABSTRACT

Alzheimer’s disease is one of the most devastating brain disorders of elderly humans. It is an undertreated disease becoming a major public health problem with a witness of increasing cases from the last decade. This article reviews about the increasing efforts directed for the discovery of modern etiological, clinical trials on varied cognitive and behavioural functions of brain and novel diagnostic and therapeutic development thesis for AD . The COVID-19 pandemic had a particularly detrimental effect on older population and patients with dementia, with an enormous death across the world. Hence, this review article also focusses about the morbidity and mortality rate of patients with AD.

Keywords: Alzheimer’s disease, ?-amyloid plaques, APOE.E4 Gene, Biomarkers, cognitive impairment, Gene therapy, COVID-19.


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