Abstract
A REVIEW ON FAST DISINTEGRATING TABLETS

Sudarshan B. Borse*, Avish D. Maru, Rajendra K. Surawase, Santosh S. Surana, Mayur M. Sonawane, Shruti V. Raundal, Vaishnavi S. Sake

ABSTRACT

Tablet formulations are preferred primarily because of their lower manufacturing costs, packaging, shipping and increased stability. Recently fast dissolving drug delivery system are starting to become popular and are being acceptances as new drug delivery system. Some tablets are designed to dissolve very quickly in saliva within seconds and are actually fast dissolving tablets. Others contain agents that increase the rate of disintegration of tablets in the mouth and can take up to a minute to completely disintegrate, which is why they are better known as fast disintegrating tablets. Older people usually have difficulty in swallowing conventional dosage forms (tablets, capsules, solutions and suspensions) due to tremors in the limbs and impaired speech (dysphasia). A fast-disintegrating drug dissolution system can solve this problem. FDTs formulations contain super disintegrant to increase the speed of tablet disintegration in the oral cavity. FDT is rapidly disintegrated and absorbed faster. In this review contain brief information about FDTs including definition, advantages, disadvantages, limitation, ideal properties, quiet characteristics, drug selection criteria, mechanism, requirement, excipient selection, methodologies, and FDT evaluation, etc.

Keywords: Fast dissolving tablets, Fast disintegrating tablets, FDT, Superdisintegrants.


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