BERGENIA LIGULATA WALL: ITS CHEMICAL CHARACTERIZATION AND PHARMACOLOGICAL POTENTIAL – A REVIEW
Megha S. Shah*, Aditi Vaidya, Tejas Kakade, Kajal Raskar and Abhisek Tathe
ABSTRACT
Bergenia ligulata Wall also known as Paashanbheda (which means ‘to dissolve stones’) is a very important medicinal herb and is considered as an example of controversial drug in the Indian System of Medicine. On phytochemical screening, it shows presence of various chemical constituents or secondary metabolites like, coumarins, flavonoids, benzenoids, lactones, etc. It shows a wide range of pharmacological activities with the main ones being, antiurolithic, antiviral, free radical scavenging, antidiabetic, hepatoprotective, diuretic, anti-inflammatory, cardioprotective and antipyretic. This review provides a detailed description of and throws insight on the pharmacognosy, phytochemistry, phytochemical standards, characterization of phytoconstituents, pharmacological activities and marketed formulations that are available in the market of Bergenia ligulata. It contains information collected from scientific journals, books and reports by visiting a library and electronic search (Science Direct, Google Scholar, etc.). This review will be helpful in the further investigation of Bergenia ligulata.
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