ROLE OF SINGLE PRE-OPERATIVE DOSE OF DEXAMETHASONE IN CONTROLLING POST OPERATIVE PAIN FOLLOWING TONSILLECTOMY: A HOSPITAL BASED COMPARATIVE STUDY
Dr. Riddhi Nayak*, Dr. Sankari Roy and Dr. Prabir Kumar Saha
ABSTRACT
Aim: To determine the efficacy of single dose of Dexamethasone (0.5mg/kg) in reducing the post-operative pain following Tonsillectomy operation. Settings and Design: A hospital based analytical (comparative) study was conducted in Department of ENT, TMC & Dr. BRAM Teaching Hospital, Hapania, Agartala, West Tripura for a duration of 3 months (October to December, 2021) after the approval from Institutional Ethics Committee. Method and Materials: A total of 40 patients with recurrent attacks of acute tonsillitis or with Chronic Tonsillitis and in need of surgical treatment were included in the study. An alternate sequential entry was made into two groups. Group 1 (Treatment group) received single dose of intravenous Inj. Dexamethasone (0.5mg/kg) pre-operatively while Group 2 (Control Group) received similar amount of Normal saline. Surgical procedure, anesthetic protocol and post-operative medications were standardized in both the groups. Post-operative pain assessment was done at 12, 24 and 48 post-operative hours using Visual analogue scale (0-10) and compared between two groups. Statistical analysis used: 2 sample independent t- test was used to compare means and standard deviation between two groups. Result: Mean pain score was significantly lower in treatment group compared to control group at 12th post-operative hour (t value = -15.739), at 24th post-operative hour (t-value = -13.161) and at 48th post-operative hour (t-value = -8.110) with p-value being 0.000 (highly significant) at all three observation periods. Conclusion: Single dose of Inj. Dexamethasone (0.5mg/kg) administered intravenously in pre-operative period is efficacious in controlling Post-operative pain following Tonsillectomy operation.
Keywords: Dexamethasone; Tonsillectomy; Post-operative pain; Anesthesia.
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