Pravin Sanjay Sake*, Dr. Manoj S. Charade and Varsha Vasant Kamble


The process of drug discovery can be described as the identification and validation of a target disease and target interact with that chemical compound in discovery and development. This interaction may be inhibit, foster or otherwise change the activity of the target. Development of drug involves fulfilled all requirements that have to be met before a new compound can be consider as ready for testing in the first time for human subjects. Testing of drug is done by preclinical and clinical trials.[1] The pharmaceutical industry on research-based has increasingly due use of modern medicinal chemistry methods, such as molecular modelling, the structure-activity relationships (SAR) can study by these powerful tool. These methodologies also used to study the pharmacodynamics data (e.g., selectivity, affinity, efficacy, potency) as well as pharmacokinetic properties (ADMET: absorption, distribution, metabolism, excretion and toxicity). The field has progressed due to advances in bio molecular spectroscopic methods such as X-ray crystallography and nuclear magnetic resonance (NMR), which have enabled striking progress in molecular and structural biology. These spectroscopic methods which have allowed to more than 100,000 the resolve three-dimensional molecular protein target structures that means providing crucial structural information about drug targets of macromolecule. Both academia and industry SBDD and LBDD approaches have been applied as valuable drug discovery tools. These approaches has been successfully employed in a number of investigations due to structural, chemical and biological data.[1,2] Heterocyclic chemistry is one of the branch of chemistry dealing with synthesis, properties, and applications of heterocyclic compound. Heterocyclic chemistry began in the 1800s, in 1818 something developing: in 1832 isolation of alloxan from uric acid by Brugnatelli, obtaining the furan by reaction with sulphuric acid in 1832s, dry distillation used for obtaining of Pyrrolin 1834.

Keywords: Drug Discovery, Heterocyclic Chemistry etc.

[Full Text Article]   [Download Certificate]


Forgot Password  |  Register


Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation


    MAY 2024 Issue has been successfully launched on 1 MAY 2024.

  • EJBPS New Impact Factor

    EJBPS Impact Factor has been Increased to 7.482 for Year 2024.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.


  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.


UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS


Copyright From

Covering Letter

                        Author Instruction