Abstract
THE REWARD DEFICIENCY SYNDROME (RDS) PARADIGM – RDS IS THE PHENOTYPE: ADDICTION AND MENTAL DISORDER ARE ENDOTYPES: ELLE FOUNDATION RESEARCH INSTITUTE 100S SERIES, FAMILY GENERATIONAL GENOMIC CASE SERIES STUDY #103.

Elizabeth Dale Gilley*

ABSTRACT

Both quantitative and qualitative observation are used for statistical analysis of the Reward Deficiency Syndrome phenotype, neurogenetic predisposition, for addiction and mental disorder endotypes, in this level 4 evidence, case series. In continuation of the Elle Foundation, 100 research series, Case Series 103 builds upon Case Study 101, in which we introduced the longitudinal study of our proband[1-2]; and Case Series 102[3] in which we compared biological sisters’ underlying neurogenetic predisposition for Reward Deficiency Syndrome (RDS). Case study series 103 observes a four generational family for polymorphic gene variances which predispose risk for Reward Deficiency Syndrome (RDS)[4-5] and compares reported lifespan experience of Diagnostic Statistical Manual of Mental Disorder (DSM).[6] Data was collected using personal interview, self-report, personality testing, the RDSQ29[7] and Genetic Addiction Risk Severity (GARS).[8] Result findings support the hypothesis that the proband’s polymorphic variances are shared by other family members, adding to the international body of evidence that RDS is a family disease, which should be treated as a frontline modality[9], on a continuum of care[10-11], beginning with Primary Physicians.[12] GARS testing for SUD patients, family members and the next generation of children is advised.

Keywords: Reward Deficiency Syndrome, Genomic Addiction Medicine, Precision Behavioral Medicine, Neurogenetics, Dopamine Homeostasis, Genetic Addiction Risk Severity (GARS).


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: AUGUST ISSUE PUBLISHED

    AUGUST 2022 Issue has been successfully launched on 1 August 2022.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT