European Journal of Biomedical and Pharmaceutical Sciences

TYPE II POLYGLANDULAR AUTOIMMUNE SYNDROME PRESENTED WITH DIABETIC KETOACIDOSIS; A RARE CASE

Singh Jitendra*, Gupta K. Kamlesh, Dinkar Anju, Himanshu D. and Atam Virendra

ABSTRACT

Type II polyglandular autoimmune syndrome is characterized by two or more of the endocrinopathies. Commonly involved endocrinopathies are primary adrenal insufficiency, Graves' disease or autoimmune hypothyroidism, type 1 diabetes mellitus and primary hypogonadism. We reported a 22 years old female with autoimmune hypothyroidism, primary adrenal insufficiency, vitiligo, alopecia and insulin dependent diabetes mellitus who was diagnosed as a case of PGA type II syndrome. It is important to highlight, if a patient has an autoimmune disease that should be screen for other autoimmune conditions. This patient was improved on thyroxine, insulin and steroid replacement therapy.

Keywords: Type II polyglandular autoimmune syndrome, Autoimmune hypothyroidism, Insulin dependent diabetes mellitus, Vitiligo, Alopecia.