European Journal of Biomedical and Pharmaceutical Sciences

A STUDY ON DRUG UTILIZATION EVALUATION IN PATIENTS WITH CHRONIC KIDNEY DISEASE COVERING THE MEDICAL AND NON-MEDICAL TREATMENTS

Mohammed Safi Ur Rahman*, Sumaiya Tabassum, Alekhya Mandepudi, Syed Abdul Hadi Ghazanfar, Zehra Fatima and Dr. B Sudhakar

ABSTRACT

Aim: To carry out a retrospective observational study, evaluate the process of drug use in patients with CKD and events covering the medical and non-medical determinants of drug utilization. This study has highlighted the drug use pattern in management of patients with CKD and to evaluate and ensure rational drug use, and also analyze medication related problems. Methodology: The study included all patients who had CKD, met inclusions criteria. 120 patients were included in the study. Convenient enrollment technique was employed in which all patients in Nephrology In-patient unit who were selectively observed with pharmaceutical care in tertiary Hospital were enrolled for a duration of 6 months. Result: The study showed prevalence of hospitalized CKD patients, various aspects affecting CKD prevalence and Drug Utilization Review in CKD patients. According to the study, the prevalence of Stage 5 CKD was higher. The study report’s prescribing trends of different drugs prescribed in the management of CKD following the guidelines given by NKF KDIGO. Majority of the drug related problems were identified in Stage 5. Drug-drug interactions (60.3%) were the most common type of DRP’S. Conclusion: The prevalence of CKD stage 5 was higher. Poly-pharmacy was found to be a potential risk for developing drug related problems. Developing and adopting the guidelines regarding drug administration, dispensing and prescribing would minimize the drug related problems in patients with CKD.

Keywords: CKD, Nephrology, drug use pattern.